The Chemistry department of S.P. Sanstha's, Sangamner College was established in 1967. This is one of the largest Science Department of the College. The Department of Chemistry has grown considerably in its history of 53 years. The Department is located near the administration building. The Department offers the courses of B. Sc. Chemistry, B.Voc. in Agriculture and Soil Sciences, B.Voc. in Dairy Products and Processing at UG Ievel. The average strength of the undergraduate class is nearly 700. A non-grant course in M. Sc. Organic Chemistry started in 1995. Later on, the M. Sc. Analytical Chemistry course also started in 2007. The average strength of the postgraduate class is 192.

There are experienced and well-qualified faculty members for UG and PG classes. In the last few years, faculty members of the Department completed around 21 major, minor and mini-research projects funded by UGC, BCUD, and S.P. Sanstha. Two faculties are recognized as research guides of Savitribai Phule Pune University. The Department has a recognized Research Centre for Chemistry. Twelve students have been awarded Ph.D. Degree and 03 students are doing their Ph.D. in this Research Centre. The Department has successfully organized 02 International and 04 National conferences. Many Eminent Professors like Prof. S. T. Shewante, Dr. V. S. Patil, Dr. P. T. Kulkarni, Dr. R. D. Pokharkar, Prof. R. D. Advant, Prof. G. D. Barde, Prof. S. R. patil, Dr. D. B. Gujarathi, Dr. K. K. Deshmukh (Ex-Principal) have worked in this Department. Presently Dr. M. S. More is working as Head of Department.

All faculty members are involved in different research areas like Heterocyclic Chemistry, Medicinal Chemistry, Phytochemistry, Natural products, Extraction process etc. More than 100 research papers have been published in reputed journals and three National and one International patents. Many students of the Department carry out their projects in a SRS Project Competition by S.P. Sanstha. The Department has received grants of 48 lakhs from DST-FIST and DBT, New Delhi. Department has well-equipped and well-furnished spacious laboratories with various sophisticated research instruments and equipments like FTIR, Rotary evaporator, UV visible spectrophotometer, Digital melting point apparatus, Parallel reaction station, Microwave etc.

Students from our Department have achieved many awards at the SPPU level like Ms. Yogini Gujarathi recieved Second prize at State Level Avishkar competition in 2007-08, Ms. Vidya Gunjal achieved first rank in B.Sc. Chemistry at SPPU in 2011-12. Mr. Yogesh Kahandal achieved seventh rank in B.Sc. Chemistry at SPPU in 2015-16. Ms. Punam Rokade achieved third rank in B.Sc. Chemistry at SPPU level in 2016-17. Ms. Priyanka Vaidya got 'Tyagmurti Shrimati Saraswati Ramchandra Shelar Gold Medal' for all round performance in 2013-14. Faculty members of the Department have also received many awards such as Best teacher, Emeritus professor, Best innovative teacher etc. from SPPU and other organizations. The Department organizes Campus interviews, NET/SET workshop for M.Sc. students, Workshop for Soil and Water testing for farmers etc. every year.

Courses run by the department